Independent Publications
6.
A. Maliori, T. Athanasiadou, V. Psomiadou, G. G. Bagkavou, C. I. Stathakis. Syntheses of ent-Aquilanol A and ent-Aquilanol B via Retro-cycloisomerization of (-)-Caryophyllene Oxide. Access to Medium-sized Oxygenated Carbocyclic Scaffolds, Org. Letters 2022, 24, 6242-6246.
5.
N. S. Iordanidis, A. L. Zografos, J. K. Gallos, T. V. Koftis, C. I. Stathakis. Continuous Flow Organocatalytic Chlorination of Alkenes Eur. J. Org. Chem. 2021, 5058–5062.
4.
S. A. Zisopoulou, S. Bousis, J. Haupenthal, J. Herrmann, R. Müller, A. K. H. Hirsch, D. Komiotis, J. K. Gallos, C. I. Stathakis. Synthesis and Biological Evaluation of Novel 2-Substituted Analogues of Pentenomycin I, Synlett 2020, 31, 475–481
3.
C. I. Stathakis, P. L. Gkizis, E. S. Alexandraki, S. Trakossas, M. Terzidis, E. Neokosmidis, C. K. Zacharis, C. Vasiliadou, E. Vastardi, T. Andreou, A. Zitrou, A.-A. Varvogli, and T. V. Koftis. (Chloromethyl) dimethylchlorosilane-KF a two-step solution to the selectivity problem in the methylation of a pyrimidone intermediate en route to raltegravir. Org. Proc. Res. Dev., 2017, 21, 1413.
2.
C. I. Stathakis, P. L. Gkizis, A. L. Zografos. Metal-catalyzed cycloisomerization as a powerful tool in the synthesis of complex sesquiterpenoids. Nat. Prod. Rep., 2016, 33, 1093.
1.
C. I. Stathakis, E. Neokosmidis, T. V. Koftis. A scalable synthesis of the antidepressant agomelatine by a tandem allylic chlorination–isomerization process. Eur. J. Org. Chem. 2014, 6376.
Supervised Publications
17.
Air-stable solid aryl and heteroaryl organozinc pivalates: Syntheses and applications in organic synthesis. S. M. Manolikakes, M. Ellwart, C. I. Stathakis, P. Knochel Chem. Eur. J. 2014, 20, 12289.
16.
Harnessing quinone methides: Total synthesis of (±)-Vaticanol A. T. H. Jepsen, S. B. Thomas, Y. Lin, C. I. Stathakis, I. de Miguel, S. A. Snyder Angew. Chem., Int. Ed. 2014, 53, 6747. Editor’s choice as Very Important Paper
15.
Synthesis of solid 2-pyridylzinc reagents and their application in Negishi reactions J. R. Colombe, S. Bernhardt, C. I. Stathakis, S. L. Buchwald, P. Knochel Org. Lett. 2013, 15, 5754.
14.
TMPZnOPiv•LiCl: A New Base for the Preparation of Air-Stable Solid Zinc Pivalates of Sensitive Aromatics and Heteroaromatics. C. I. Stathakis, S. M. Manolikakes, P. Knochel Org. Lett. 2013, 15, 1302.
13.
Improved Air-Stable Solid Aromatic and Heterocyclic Zinc Reagents by Highly Selective Metalations for Negishi Cross-Couplings. C. I. Stathakis, S. Bernhardt, V. Quint, P. Knochel Angew. Chem., Int. Ed. 2012, 51, 9428.
12.
Total syntheses of (-)-a-Kainic Acid. C. I. Stathakis, E. G. Gioti, J. K. Gallos Eur. J. Org. Chem. 2012, 4661.
10 Most accessed articles in EurJOC in 09/2012.
25 Most Accessed articles in EurJOC between 10/2011-09/2012.
10 Most accessed articles in EurJOC in 09/2012.
25 Most Accessed articles in EurJOC between 10/2011-09/2012.
11.
Synthesis of 5,6-spiro ethers and evaluation of their affinity for the bacterial A-site. I. A. Katsoulis, G. Kythreoti, A. Papakyriakou, K. Koltsida, P. Anastasopoulou, C. I. Stathakis, I. Mavridis, T. Cottin, E. Saridakis, D. Vourloumis ChemBioChem 2011, 12, 1188.
10.
Designed spiro-bicyclic analogues targeting the bacterial ribosome. T. Cottin, C. Pyrkotis, C. I. Stathakis, I. Mavridis, I. A. Katsoulis, P. Anastasopoulou, G. Kythreoti, A. L. Zografos, V. R. Nahmias, A. Papakyriakou, D. Vourloumis ChemBioChem 2011, 12, 71.
9.
Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome. C. I. Stathakis, I. Mavridis, G. Kythreoti, A. Papakyriakou, I. A. Katsoulis, T. Cottin, P. Anastasopoulou, D. Vourloumis Biorg. Med. Chem. Lett. 2010, 20, 7488.
8.
Synthesis of ent-Gabosine E from d-mannose by intramolecular nitrone–olefin cycloaddition. C. I. Stathakis, M. N. Athanatou, J. K. Gallos Tetrahedron Lett. 2009, 50, 6916.
7.
Synthesis of enantiomericaly pure γ-lactones from 2,3-O-isopropylidene-D- or L-Erythrose.S. M. Totokotsopoulos, E. E. Anagnostaki, C. I. Stathakis, E. G. Yioti, C. Z. Hadjimichael, J. K. Gallos ARKIVOC 2009, (x), 209.
6.
Traceless Solid Phase Synthesis of Chiral Hydroxylated Cyclopentenones. C. I. Stathakis, J. K. Gallos Tetrahedron Lett. 2008, 49, 6804.
5.
Convenient Preparations of 2-Alkyl-5-oxopyrrolidine-3-carboxylic Acids.A. D. Photiadou, C. I. Stathakis, J. K. Gallos J. Heterocyclic Chem. 2008, 45, 1251.
4.
Efficient Synthesis of (±)-N-Boc-pregabalin via Hetero-Diels-Alder Addition of Methyl 3-Nitrosoacrylate to Ethyl Vinyl Ether.J. K. Gallos, E. S. Alexandraki, C. I. Stathakis Heterocycles, 2007, 71, 1127.
3.
A Short and Alternative Preparation of the Bengazoles Polyol Side-chain Segment.J. K. Gallos, C. I. Stathakis, C. E. Grammatoglou, M. J. Salapassidou, A. E. Koumbis Carbohydr. Res., 2007, 342,744.
2.
An Improved Approach to Chiral Cyclopentenone Building Blocks. Total Synthesis of Pentenomycin I and Neplanocin A.J. K. Gallos, C. I. Stathakis, S. S. Kotoulas, A. E. Koumbis J. Org. Chem. 2005, 70, 6884.
1.
Hetero-Diels-Alder Additions to Pent-4-enofuranosides: Concise Synthesis of Hydroxylated Pyrrolizidines.J. K. Gallos, V. C. Sarli, C. I. Stathakis, T. V. Koftis, V. R. Nachmia, E. Coutouli-Argyropoulou Tetrahedron 2002, 58, 9351.
Patents
5.
A novel process for the preparation of Tapentadol. P. L. Gkizis, T. V. Koftis, E. Neokosmidis, T. Panagiotidis, C. I. Stathakis, WIPO, 2019, WO2019238269A1.
4.
Process for preparing Tapentadol oxalate.T. V. Koftis, E. Neokosmidis, C. I. Stathakis, P. L. Gkizis, E. A. A. Varvogli, EPO, 2018, PCT/EP2018/025468
3.
Process for preparing compounds useful as intermediates for the preparation of raltegravir. T. V. Koftis, E. Neokosmidis, C. I. Stathakis, P. L. Gkizis, E. Alexandraki, S. Trakossas, M. Terzidis, A. Lithadioti, A.-A. Varvogli, WIPO, 2017, WO2017220208A1
2.
Methods for the preparation of topiroxostat and intermediates thereof. T. V. Koftis, E. Neokosmidis, C. I. Stathakis, T. Andreou, C. Raptis, P. L. Gkizis, WIPO, 2016, WO2016134854A1
1.
A novel process for the preparation of tetralin and naphthalene derivatives.T. V. Koftis, E. Neokosmidis, C. I. Stathakis, T. Andreou, C. Raptis, A.-A. Varvogli, WIPO, 2015, WO2015000555A2